SCOPe 2.03: Domain d3dwha_: 3dwh A:

Lineage for d3dwha_ (3dwh A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.122: PUA domain-like [88696] (1 superfamily)
   pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other

4. Superfamily b.122.1: PUA domain-like [88697] (14 families)

5. Family b.122.1.12: SRA domain-like [159368] (2 proteins)
   Pfam PF02182; recognizes the modified cytosine base (m5C) by flipping it out of DNA

6. Protein E3 ubiquitin-protein ligase UHRF1 [159369] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159370] (4 PDB entries)
   Uniprot Q96T88 409-615! Uniprot Q96T88 414-617

8. Domain d3dwha_: 3dwh A: [157912]
   automated match to d3bi7a1
   complexed with gol, so4

Details for d3dwha_

PDB Entry: 3dwh, 1.95 Å

PDB Description: Structural and Functional Analysis of SRA domain

PDB Compounds: (A:) E3 ubiquitin-protein ligase UHRF1

SCOPe Domain Sequences for d3dwha_:

Sequence, based on SEQRES records:

>d3dwha_ b.122.1.12 (A:) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
gshmpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyedd
vdhgnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrs
gkpvrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgp
wtkegkdrikklgltmqypegylea

Sequence, based on observed residues (ATOM records):

>d3dwha_ b.122.1.12 (A:) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
gshmpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyedd
vdhgnfftytgsggscdqkltntnralalncfapindqegaeakdwrsgkpvrvvrnvkg
gknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegkdrikkl
gltmqypegylea

Timeline for d3dwha_:

• d3dwha_ first appeared in SCOP 1.75, called d3dwha1
  
• d3dwha_ appears in SCOPe 2.02
  
• d3dwha_ appears in SCOPe 2.04
  
• d3dwha_ appears in the current release, SCOPe 2.08, called d3dwha2