SCOPe 2.01: Domain d3dvna2: 3dvn A:110-214

Lineage for d3dvna2 (3dvn A:110-214)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (132 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d3dvna2: 3dvn A:110-214 [157895]
   Other proteins in same PDB: d3dvna1, d3dvnb1, d3dvnb2, d3dvnh1, d3dvnh2, d3dvnl1, d3dvnu_, d3dvnv_, d3dvnx_, d3dvny_
   automatically matched to d1g9ml2

Details for d3dvna2

PDB Entry: 3dvn, 2.7 Å

PDB Description: crystal structure of k63-specific fab apu2.16 bound to k63-linked di- ubiquitin

PDB Compounds: (A:) Human IgG1 fab fragment light chain

SCOPe Domain Sequences for d3dvna2:

Sequence; same for both SEQRES and ATOM records:

>d3dvna2 b.1.1.2 (A:110-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrg

Timeline for d3dvna2:

• d3dvna2 first appeared in SCOP 1.75
  
• d3dvna2 appears in SCOPe 2.02
  
• d3dvna2 appears in the current release, SCOPe 2.08