SCOPe 2.04: Domain d3dlkb_: 3dlk B:

Lineage for d3dlkb_ (3dlk B:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (145 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d3dlkb_: 3dlk B: [157774]
   Other proteins in same PDB: d3dlka2
   automated match to d1lweb_
   complexed with so4

Details for d3dlkb_

PDB Entry: 3dlk, 1.85 Å

PDB Description: crystal structure of an engineered form of the hiv-1 reverse transcriptase, rt69a

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d3dlkb_:

Sequence, based on SEQRES records:

>d3dlkb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyq

Sequence, based on observed residues (ATOM records):

>d3dlkb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwelgiphpaglkkkksvtvldvgdayfsvpldedfrky
taftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddl
yvgsdleigqhrtkieelrqhllrwgpflwmgyelhpdkwtvqpivlpekdswtvndiqk
lvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyy
dpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittes
iviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d3dlkb_:

• d3dlkb_ first appeared in SCOP 1.75, called d3dlkb1
  
• d3dlkb_ appears in SCOPe 2.03
  
• d3dlkb_ appears in SCOPe 2.05
  
• d3dlkb_ appears in the current release, SCOPe 2.08