SCOP 1.75: Domain d3di6a1: 3di6 A:5-440

Lineage for d3di6a1 (3di6 A:5-440)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (111 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582
   Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584
   Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d3di6a1: 3di6 A:5-440 [157743]
   automatically matched to d1c1cb_
   complexed with pdz

Details for d3di6a1

PDB Entry: 3di6, 2.65 Å

PDB Description: HIV-1 RT with pyridazinone non-nucleoside inhibitor

PDB Compounds: (A:) Reverse transcriptase/ribonuclease H

SCOP Domain Sequences for d3di6a1:

Sequence, based on SEQRES records:

>d3di6a1 e.8.1.2 (A:5-440) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyqlekepivgaetf

Sequence, based on observed residues (ATOM records):

>d3di6a1 e.8.1.2 (A:5-440) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
tkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyt
aftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddly
vgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpe
kdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenre
ilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkql
teavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
lekepivgaetf

Timeline for d3di6a1:

• d3di6a1 is new in SCOP 1.75
  
• d3di6a1 appears in SCOPe 2.01
  
• d3di6a1 last appears in SCOPe 2.02