SCOPe 2.04: Domain d3d2uh2: 3d2u H:98-198

Lineage for d3d2uh2 (3d2u H:98-198)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.4: I set domains [49159] (39 proteins)

6. Protein Ligand binding domain of lir-1 (ilt2) [49206] (1 species)
   possibly an intermediate structure between the I set and FnIII domains

7. Species Human (Homo sapiens) [TaxId:9606] [49207] (5 PDB entries)
   Uniprot Q8NHL6 25-218

8. Domain d3d2uh2: 3d2u H:98-198 [157260]
   Other proteins in same PDB: d3d2ub_, d3d2uf_
   automatically matched to d1g0xa2
   complexed with bma, fuc, man, nag

Details for d3d2uh2

PDB Entry: 3d2u, 2.21 Å

PDB Description: structure of ul18, a peptide-binding viral mhc mimic, bound to a host inhibitory receptor

PDB Compounds: (H:) Leukocyte immunoglobulin-like receptor subfamily B member 1

SCOPe Domain Sequences for d3d2uh2:

Sequence, based on SEQRES records:

>d3d2uh2 b.1.1.4 (H:98-198) Ligand binding domain of lir-1 (ilt2) {Human (Homo sapiens) [TaxId: 9606]}
ayikptlsaqpspvvnsggnvtlqcdsqvafdgfilckegedehpqclnsqphargssra
ifsvgpvspsrrwwyrcyaydsnspyewslpsdllellvlg

Sequence, based on observed residues (ATOM records):

>d3d2uh2 b.1.1.4 (H:98-198) Ligand binding domain of lir-1 (ilt2) {Human (Homo sapiens) [TaxId: 9606]}
ayikptlsaqpspvvnsggnvtlqcdsqvafdgfilckegeqclnsraifsvgpvspsrr
wwyrcyaydsnspyewslpsdllellvlg

Timeline for d3d2uh2:

• d3d2uh2 first appeared in SCOP 1.75
  
• d3d2uh2 appears in SCOPe 2.03
  
• d3d2uh2 appears in SCOPe 2.05
  
• d3d2uh2 appears in the current release, SCOPe 2.08