SCOPe 2.03: Domain d3clza_: 3clz A:

Lineage for d3clza_ (3clz A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.122: PUA domain-like [88696] (1 superfamily)
   pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other

4. Superfamily b.122.1: PUA domain-like [88697] (14 families)

5. Family b.122.1.12: SRA domain-like [159368] (2 proteins)
   Pfam PF02182; recognizes the modified cytosine base (m5C) by flipping it out of DNA

6. Protein E3 ubiquitin-protein ligase UHRF1 [159369] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159370] (4 PDB entries)
   Uniprot Q96T88 409-615! Uniprot Q96T88 414-617

8. Domain d3clza_: 3clz A: [156766]
   automated match to d3bi7a1

Details for d3clza_

PDB Entry: 3clz, 2.2 Å

PDB Description: The set and ring associated (SRA) domain of UHRF1 bound to methylated DNA

PDB Compounds: (A:) E3 ubiquitin-protein ligase UHRF1

SCOPe Domain Sequences for d3clza_:

Sequence; same for both SEQRES and ATOM records:

>d3clza_ b.122.1.12 (A:) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
nhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvdhgnf
ftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwrsgkpvrv
vrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegk
drikklgltmqypegylealanah

Timeline for d3clza_:

• d3clza_ first appeared in SCOP 1.75, called d3clza1
  
• d3clza_ appears in SCOPe 2.02
  
• d3clza_ appears in SCOPe 2.04
  
• d3clza_ appears in the current release, SCOPe 2.08, called d3clza2