SCOP 1.75: Domain d3cfjl2: 3cfj L:108-212

Lineage for d3cfjl2 (3cfj L:108-212)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (132 PDB entries)
   SQ NA # humanized antibody
   Uniprot P01834 # KAC_HUMAN Ig kappa chain C region
   SQ P01834 # KAC_HUMAN Ig kappa chain C region.
   SQ NA # engineered antibody
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d3cfjl2: 3cfj L:108-212 [156580]
   Other proteins in same PDB: d3cfja1, d3cfjb1, d3cfjb2, d3cfjc1, d3cfjd1, d3cfjd2, d3cfje1, d3cfjf1, d3cfjf2, d3cfjh1, d3cfjh2, d3cfjl1
   automatically matched to d1g9ml2
   complexed with gol, so4; mutant

Details for d3cfjl2

PDB Entry: 3cfj, 2.6 Å

PDB Description: crystal structure of catalytic elimination antibody 34e4, orthorhombic crystal form

PDB Compounds: (L:) Catalytic Antibody Fab 34E4 Light chain

SCOP Domain Sequences for d3cfjl2:

Sequence; same for both SEQRES and ATOM records:

>d3cfjl2 b.1.1.2 (L:108-212) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrg

Timeline for d3cfjl2:

• d3cfjl2 is new in SCOP 1.75
  
• d3cfjl2 appears in SCOPe 2.01
  
• d3cfjl2 appears in the current release, SCOPe 2.08