Lineage for d3cfjb1 (3cfj B:1-113)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1287638Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1287816Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (33 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)
  8. 1287835Domain d3cfjb1: 3cfj B:1-113 [156567]
    Other proteins in same PDB: d3cfja1, d3cfja2, d3cfjb2, d3cfjc1, d3cfjc2, d3cfjd2, d3cfje1, d3cfje2, d3cfjf2, d3cfjh2, d3cfjl1, d3cfjl2
    automatically matched to d1aqkh1
    complexed with gol, so4

Details for d3cfjb1

PDB Entry: 3cfj (more details), 2.6 Å

PDB Description: crystal structure of catalytic elimination antibody 34e4, orthorhombic crystal form
PDB Compounds: (B:) Catalytic Antibody Fab 34E4 Heavy chain

SCOPe Domain Sequences for d3cfjb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3cfjb1 b.1.1.1 (B:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 3 [TaxId: 9606]}
evkllesggglaqpggslklscaasgfdfrrywmtwvrqapgkglewigeinpdsrtiny
mpslkdkfiisrdnaknslylqlsrlrsedsalyycvrldfdvynhyyvldywgqgtsvt
vss

SCOPe Domain Coordinates for d3cfjb1:

Click to download the PDB-style file with coordinates for d3cfjb1.
(The format of our PDB-style files is described here.)

Timeline for d3cfjb1: