Lineage for d3c2sa2 (3c2s A:340-445)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 785963Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589] (5 species)
  7. 785966Species Human (Homo sapiens) [TaxId:9606] [88590] (28 PDB entries)
    Uniprot P01857 #118-327
    Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region
    Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region
  8. 785974Domain d3c2sa2: 3c2s A:340-445 [155886]
    Other proteins in same PDB: d3c2sa1
    automatically matched to d1hzhh4
    complexed with bma, fuc, gal, man, nag, zn; mutant

Details for d3c2sa2

PDB Entry: 3c2s (more details), 2.3 Å

PDB Description: Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions
PDB Compounds: (A:) IGHM protein

SCOP Domain Sequences for d3c2sa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3c2sa2 b.1.1.2 (A:340-445) Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma {Human (Homo sapiens) [TaxId: 9606]}
kgqprepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvld
sdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslsp

SCOP Domain Coordinates for d3c2sa2:

Click to download the PDB-style file with coordinates for d3c2sa2.
(The format of our PDB-style files is described here.)

Timeline for d3c2sa2:

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Domains from same chain:
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d3c2sa1