SCOPe 2.04: Domain d3c09d2: 3c09 D:481-500

Lineage for d3c09d2 (3c09 D:481-500)

1. Root: SCOPe 2.04

2. Class g: Small proteins [56992] (91 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.9: Growth factor receptor domain [57184] (2 families)

5. Family g.3.9.1: Growth factor receptor domain [57185] (9 proteins)

6. Protein EGF receptor Cys-rich domains [82887] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82888] (6 PDB entries)

8. Domain d3c09d2: 3c09 D:481-500 [155816]
   Other proteins in same PDB: d3c09a1, d3c09c1, d3c09c2, d3c09d1, d3c09h1, d3c09h2
   automatically matched to d1ivoa4
   complexed with bma, man, nag

Details for d3c09d2

PDB Entry: 3c09, 3.2 Å

PDB Description: crystal structure the fab fragment of matuzumab (fab72000) in complex with domain iii of the extracellular region of egfr

PDB Compounds: (D:) Epidermal growth factor receptor

SCOPe Domain Sequences for d3c09d2:

Sequence; same for both SEQRES and ATOM records:

>d3c09d2 g.3.9.1 (D:481-500) EGF receptor Cys-rich domains {Human (Homo sapiens) [TaxId: 9606]}
vchalcspegcwgpeprdcv

Timeline for d3c09d2:

• d3c09d2 first appeared in SCOP 1.75
  
• d3c09d2 appears in SCOPe 2.03
  
• d3c09d2 appears in SCOPe 2.05
  
• d3c09d2 appears in the current release, SCOPe 2.08