Lineage for d3bhta1 (3bht A:1-298)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874554Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 874564Species Human (Homo sapiens) [TaxId:9606] [88856] (128 PDB entries)
    Uniprot P24941
  8. 874581Domain d3bhta1: 3bht A:1-298 [155276]
    Other proteins in same PDB: d3bhtb1, d3bhtb2, d3bhtd1, d3bhtd2
    automatically matched to d1vywa_
    complexed with mfr, mg, sgm

Details for d3bhta1

PDB Entry: 3bht (more details), 2 Å

PDB Description: Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3
PDB Compounds: (A:) Cell division protein kinase 2

SCOP Domain Sequences for d3bhta1:

Sequence, based on SEQRES records: (download)

>d3bhta1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d3bhta1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtegvpstaireisllkelnhpn
ivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshr
vlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyyst
avdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpk
warqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOP Domain Coordinates for d3bhta1:

Click to download the PDB-style file with coordinates for d3bhta1.
(The format of our PDB-style files is described here.)

Timeline for d3bhta1: