SCOPe 2.01: Domain d2zlaa_: 2zla A:

Lineage for d2zlaa_ (2zla A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [101432] (15 PDB entries)

8. Domain d2zlaa_: 2zla A: [154627]
   automated match to d1rkha_
   protein/DNA complex; complexed with vdb

Details for d2zlaa_

PDB Entry: 2zla, 2 Å

PDB Description: 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation and crystal structure

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d2zlaa_:

Sequence, based on SEQRES records:

>d2zlaa_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrmdgstgsvtldlsplsmlphladl
vsysiqkvigfakmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdy
kydvtdvskaghtlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklve
aiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmk
ltplvlevfgn

Sequence, based on observed residues (ATOM records):

>d2zlaa_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrplsmlphladlvsysiqkvigfak
mipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskaght
lelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlqty
ircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmkltplvlevfgn

Timeline for d2zlaa_:

• d2zlaa_ first appeared in SCOP 1.75, called d2zlaa1
  
• d2zlaa_ appears in SCOPe 2.02
  
• d2zlaa_ appears in the current release, SCOPe 2.08