SCOP 1.75: Domain d2z93d2: 2z93 D:108-205

Lineage for d2z93d2 (2z93 D:108-205)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (318 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity
   SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region)
   Uniprot P01837 # KAC_MOUSE Ig kappa chain C region
   Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region
   SQ NA # part of Fab 28 against HIV-1 RT
   Uniprot P01837 #
   KAC_MOUSE Ig kappa chain C region
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d2z93d2: 2z93 D:108-205 [154231]
   Other proteins in same PDB: d2z93a1, d2z93c1, d2z93d1
   automatically matched to d1dqdl2
   complexed with end

Details for d2z93d2

PDB Entry: 2z93, 2.4 Å

PDB Description: crystal structure of fab fragment of anti-ciguatoxin antibody 10c9 in complex with ctx3c-abcd

PDB Compounds: (D:) Anti-ciguatoxin antibody 10C9 Fab light chain

SCOP Domain Sequences for d2z93d2:

Sequence, based on SEQRES records:

>d2z93d2 b.1.1.2 (D:108-205) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspi

Sequence, based on observed residues (ATOM records):

>d2z93d2 b.1.1.2 (D:108-205) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkngvlnswtdqdskdstys
msstltceathktstspi

Timeline for d2z93d2:

• d2z93d2 is new in SCOP 1.75
  
• d2z93d2 appears in SCOPe 2.01
  
• d2z93d2 appears in the current release, SCOPe 2.08