SCOP 1.75: Domain d2vsrb1: 2vsr B:207-474

Lineage for d2vsrb1 (2vsr B:207-474)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (46 PDB entries)
   Uniprot P37231 232-505

8. Domain d2vsrb1: 2vsr B:207-474 [153530]
   automatically matched to d1wm0x_
   complexed with 9ho

Details for d2vsrb1

PDB Entry: 2vsr, 2.05 Å

PDB Description: hPPARgamma Ligand binding domain in complex with 9-(S)-HODE

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOP Domain Sequences for d2vsrb1:

Sequence, based on SEQRES records:

>d2vsrb1 a.123.1.1 (B:207-474) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiyk

Sequence, based on observed residues (ATOM records):

>d2vsrb1 a.123.1.1 (B:207-474) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgedkikfkhit
pkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlasl
mnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviil
sgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqll
qvikkthpllqeiyk

Timeline for d2vsrb1:

• d2vsrb1 is new in SCOP 1.75
  
• d2vsrb1 is called d2vsrb_ in SCOPe 2.01
  
• d2vsrb1 appears in the current release, SCOPe 2.08, called d2vsrb_