Lineage for d2vr4a5 (2vr4 A:331-678)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1336838Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 1339265Superfamily c.1.8: (Trans)glycosidases [51445] (15 families) (S)
  5. 1339836Family c.1.8.3: beta-glycanases [51487] (27 proteins)
    consist of a number of sequence families
  6. 1340167Protein Five-domain beta-mannosidase, domain 3 [159385] (1 species)
  7. 1340168Species Bacteroides thetaiotaomicron [TaxId:818] [159386] (9 PDB entries)
    Uniprot Q8AAK6 330-678! Uniprot Q8AAK6 331-678
  8. 1340173Domain d2vr4a5: 2vr4 A:331-678 [153499]
    Other proteins in same PDB: d2vr4a1, d2vr4a2, d2vr4a3, d2vr4a4, d2vr4b1, d2vr4b2, d2vr4b3, d2vr4b4
    automatically matched to 2JE8 A:331-678
    complexed with 17b, br, cl, edo

Details for d2vr4a5

PDB Entry: 2vr4 (more details), 1.8 Å

PDB Description: transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-d structure
PDB Compounds: (A:) beta-mannosidase

SCOPe Domain Sequences for d2vr4a5:

Sequence; same for both SEQRES and ATOM records: (download)

>d2vr4a5 c.1.8.3 (A:331-678) Five-domain beta-mannosidase, domain 3 {Bacteroides thetaiotaomicron [TaxId: 818]}
rtirvvnekdkdgesfyfevngipmfakganyipqdallpnvtteryqtlfrdmkeanmn
mvriwgggtyennlfydladengilvwqdfmfactpypsdptflkrveaeavynirrlrn
haslamwcgnneilealkywgfekkftpevyqglmhgydklfrellpstvkefdsdrfyv
hsspylanwgrpeswgtgdshnwgvwygkkpfesldtdlprfmsefgfqsfpemktiaaf
aapedyqiesevmnahqkssignslirtymerdyiipesfedfvyvglvlqgqgmrhgle
ahrrnrpycmgtlywqlndswpvvswssidyygnwkalhyqakrafap

SCOPe Domain Coordinates for d2vr4a5:

Click to download the PDB-style file with coordinates for d2vr4a5.
(The format of our PDB-style files is described here.)

Timeline for d2vr4a5: