Lineage for d2r8pb2 (2r8p B:2-332)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2122269Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2122270Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2122701Family c.36.1.10: TK-like PP module [88760] (3 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2122720Protein Transketolase (TK), PP module [88761] (4 species)
  7. 2122736Species Escherichia coli [TaxId:562] [89656] (4 PDB entries)
  8. 2122742Domain d2r8pb2: 2r8p B:2-332 [151741]
    Other proteins in same PDB: d2r8pa1, d2r8pa3, d2r8pb1, d2r8pb3, d2r8pb4
    automated match to d1qgda2
    complexed with ca, edo, t6f

Details for d2r8pb2

PDB Entry: 2r8p (more details), 1.65 Å

PDB Description: transketolase from e. coli in complex with substrate d-fructose-6- phosphate
PDB Compounds: (B:) Transketolase 1

SCOPe Domain Sequences for d2r8pb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2r8pb2 c.36.1.10 (B:2-332) Transketolase (TK), PP module {Escherichia coli [TaxId: 562]}
ssrkelanairalsmdavqkaksghpgapmgmadiaevlwrdflkhnpqnpswadrdrfv
lsnghgsmliysllhltgydlpmeelknfrqlhsktpghpevgytagvetttgplgqgia
navgmaiaektlaaqfnrpghdivdhytyafmgdgcmmegishevcslagtlklgkliaf
yddngisidghvegwftddtamrfeaygwhvirdidghdaasikraveearavtdkpsll
mcktiigfgspnkagthdshgaplgdaeialtreqlgwkyapfeipseiyaqwdakeagq
akesawnekfaayakaypqeaaeftrrmkge

SCOPe Domain Coordinates for d2r8pb2:

Click to download the PDB-style file with coordinates for d2r8pb2.
(The format of our PDB-style files is described here.)

Timeline for d2r8pb2: