SCOPe 2.04: Domain d2qo0b1: 2qo0 B:-10-174

Lineage for d2qo0b1 (2qo0 B:-10-174)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.95: Thiolase-like [53900] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest

4. Superfamily c.95.1: Thiolase-like [53901] (3 families)

5. Family c.95.1.2: Chalcone synthase-like [53914] (9 proteins)

6. Protein Ketoacyl-ACP synthase III (FabH) [53912] (3 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [64196] (12 PDB entries)

8. Domain d2qo0b1: 2qo0 B:-10-174 [150970]
   automated match to d2qnza1
   complexed with d1t; mutant

Details for d2qo0b1

PDB Entry: 2qo0, 1.85 Å

PDB Description: crystal structure of the complex between the a246f mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase iii (fabh) and 11-(decyldithiocarbonyloxy)-undecanoic acid

PDB Compounds: (B:) 3-oxoacyl-[acyl-carrier-protein] synthase 3

SCOPe Domain Sequences for d2qo0b1:

Sequence, based on SEQRES records:

>d2qo0b1 c.95.1.2 (B:-10-174) Ketoacyl-ACP synthase III (FabH) {Mycobacterium tuberculosis [TaxId: 1773]}
mteiattsgarsvgllsvgayrpervvtndeicqhidssdewiytrtgiktrrfaaddes
aasmateacrralsnaglsaadidgvivttnthflqtppaapmvaaslgakgilgfdlsa
gcagfgyalgaaadmirgggaatmlvvgteklsptidmydrgncfifadgaaavvvgetp
fqgi

Sequence, based on observed residues (ATOM records):

>d2qo0b1 c.95.1.2 (B:-10-174) Ketoacyl-ACP synthase III (FabH) {Mycobacterium tuberculosis [TaxId: 1773]}
mteiattsgarsvgllsvgayrpervvtndeicqhidewiytrtgiktrrfaaddesaas
mateacrralsnaglsaadidgvivttnthflqtppaapmvaaslgakgilgfdlsagca
gfgyalgaaadmirgggaatmlvvgteklsptidmydrgncfifadgaaavvvgetpfqg
i

Timeline for d2qo0b1:

• d2qo0b1 first appeared in SCOP 1.75
  
• d2qo0b1 appears in SCOPe 2.03
  
• d2qo0b1 appears in SCOPe 2.05
  
• d2qo0b1 appears in the current release, SCOPe 2.08