Lineage for d2qcsa1 (2qcs A:13-350)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874422Protein cAMP-dependent PK, catalytic subunit [56116] (4 species)
    AGC group; PKA subfamily; serine/threonine kinase
  7. 874459Species Mouse (Mus musculus) [TaxId:10090] [56119] (17 PDB entries)
  8. 874464Domain d2qcsa1: 2qcs A:13-350 [150656]
    automatically matched to d1l3re_
    complexed with act, anp, gol, mn, so4, tam; mutant

Details for d2qcsa1

PDB Entry: 2qcs (more details), 2.2 Å

PDB Description: a complex structure between the catalytic and regulatory subunit of protein kinase a that represents the inhibited state
PDB Compounds: (A:) cAMP-dependent protein kinase, alpha-catalytic subunit

SCOP Domain Sequences for d2qcsa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2qcsa1 d.144.1.7 (A:13-350) cAMP-dependent PK, catalytic subunit {Mouse (Mus musculus) [TaxId: 10090]}
esvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamk
ildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshl
rrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvk
grtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivs
gkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkvea
pfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

SCOP Domain Coordinates for d2qcsa1:

Click to download the PDB-style file with coordinates for d2qcsa1.
(The format of our PDB-style files is described here.)

Timeline for d2qcsa1: