SCOPe 2.06: Domain d2psqb_: 2psq B:

Lineage for d2psqb_ (2psq B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 2 [75562] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75563] (16 PDB entries)
   Uniprot P21802 467-765

8. Domain d2psqb_: 2psq B: [149828]
   automated match to d4hvsa_
   complexed with so4

Details for d2psqb_

PDB Entry: 2psq, 2.4 Å

PDB Description: Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain

PDB Compounds: (B:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d2psqb_:

Sequence, based on SEQRES records:

>d2psqb_ d.144.1.7 (B:) Fibroblast growth factor receptor 2 {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfg
lardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypg
ipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttn

Sequence, based on observed residues (ATOM records):

>d2psqb_ d.144.1.7 (B:) Fibroblast growth factor receptor 2 {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidpkeavtvavkmlkddatekdls
dlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgeeqmtf
kdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyykkt
tngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkegh
rmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttn

Timeline for d2psqb_:

• d2psqb_ first appeared in SCOP 1.75, called d2psqb1
  
• d2psqb_ appears in SCOPe 2.05
  
• d2psqb_ appears in SCOPe 2.07
  
• d2psqb_ appears in the current release, SCOPe 2.08