SCOPe 2.06: Domain d2pm8a_: 2pm8 A:

Lineage for d2pm8a_ (2pm8 A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.0: automated matches [191404] (1 protein)
   not a true family

6. Protein automated matches [190543] (91 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188340] (73 PDB entries)

8. Domain d2pm8a_: 2pm8 A: [149655]
   automated match to d2x8ba_
   complexed with gol, nag, ndg, so4

Details for d2pm8a_

PDB Entry: 2pm8, 2.8 Å

PDB Description: crystal structure of recombinant full length human butyrylcholinesterase

PDB Compounds: (A:) cholinesterase

SCOPe Domain Sequences for d2pm8a_:

Sequence, based on SEQRES records:

>d2pm8a_ c.69.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqet
qnqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkvlemtg

Sequence, based on observed residues (ATOM records):

>d2pm8a_ c.69.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdytkaeeilsrsivkrwanfakygnpqetq
nqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkvlemtg

Timeline for d2pm8a_:

• d2pm8a_ first appeared in SCOP 1.75, called d2pm8a1
  
• d2pm8a_ appears in SCOPe 2.05
  
• d2pm8a_ appears in SCOPe 2.07
  
• d2pm8a_ appears in the current release, SCOPe 2.08