SCOPe 2.03: Domain d2pb7a1: 2pb7 A:409-615

Lineage for d2pb7a1 (2pb7 A:409-615)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.122: PUA domain-like [88696] (1 superfamily)
   pseudobarrel; mixed folded sheet of 5 strands; order 13452; strand 1 and 3 are parallel to each other

4. Superfamily b.122.1: PUA domain-like [88697] (14 families)

5. Family b.122.1.12: SRA domain-like [159368] (2 proteins)
   Pfam PF02182; recognizes the modified cytosine base (m5C) by flipping it out of DNA

6. Protein E3 ubiquitin-protein ligase UHRF1 [159369] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159370] (4 PDB entries)
   Uniprot Q96T88 409-615! Uniprot Q96T88 414-617

8. Domain d2pb7a1: 2pb7 A:409-615 [149351]

Details for d2pb7a1

PDB Entry: 2pb7, 1.9 Å

PDB Description: Crystal Structure of the SRA domain of the human UHRF1 protein

PDB Compounds: (A:) E3 ubiquitin-protein ligase UHRF1

SCOPe Domain Sequences for d2pb7a1:

Sequence, based on SEQRES records:

>d2pb7a1 b.122.1.12 (A:409-615) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
ectivpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyed
dvdhgnfftytgsggrdlsgnkrtaeqscdqkltntnralalncfapindqegaeakdwr
sgkpvrvvrnvkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepg
pwtkegkdrikklgltmqypegyleal

Sequence, based on observed residues (ATOM records):

>d2pb7a1 b.122.1.12 (A:409-615) E3 ubiquitin-protein ligase UHRF1 {Human (Homo sapiens) [TaxId: 9606]}
ectivpsnhygpipgipvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyed
dvdhgnfftytgsggeqscdqkltntnralalncfapindqegaeakdwrsgkpvrvvrn
vkggknskyapaegnrydgiykvvkywpekgksgflvwryllrrdddepgpwtkegkdri
kklgltmqypegyleal

Timeline for d2pb7a1:

• d2pb7a1 first appeared in SCOP 1.75
  
• d2pb7a1 appears in SCOPe 2.02
  
• d2pb7a1 appears in SCOPe 2.04
  
• d2pb7a1 appears in the current release, SCOPe 2.08