SCOP 1.75: Domain d2pavp1: 2pav P:1-139

Lineage for d2pavp1 (2pav P:1-139)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.110: Profilin-like [55769] (10 superfamilies)
   core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha

4. Superfamily d.110.1: Profilin (actin-binding protein) [55770] (1 family)
   alpha-beta(2)-alpha-beta(5)-alpha

5. Family d.110.1.1: Profilin (actin-binding protein) [55771] (1 protein)

6. Protein Profilin (actin-binding protein) [55772] (8 species)

7. Species Human (Homo sapiens), isoform I [TaxId:9606] [55774] (9 PDB entries)

8. Domain d2pavp1: 2pav P:1-139 [149350]
   automatically matched to d1fika_
   complexed with atp, ca

Details for d2pavp1

PDB Entry: 2pav, 1.8 Å

PDB Description: Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP

PDB Compounds: (P:) Profilin-1

SCOP Domain Sequences for d2pavp1:

Sequence; same for both SEQRES and ATOM records:

>d2pavp1 d.110.1.1 (P:1-139) Profilin (actin-binding protein) {Human (Homo sapiens), isoform I [TaxId: 9606]}
agwnayidnlmadgtcqdaaivgykdspsvwaavpgktfvnitpaevgvlvgkdrssfyv
ngltlggqkcsvirdsllqdgefsmdlrtkstggaptfnvtvtktdktlvllmgkegvhg
glinkkcyemashlrrsqy

Timeline for d2pavp1:

• d2pavp1 is new in SCOP 1.75
  
• d2pavp1 is called d2pavp_ in SCOPe 2.01
  
• d2pavp1 appears in the current release, SCOPe 2.08, called d2pavp_