SCOP 1.75: Domain d2p1va1: 2p1v A:229-458

Lineage for d2p1va1 (2p1v A:229-458)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (18 PDB entries)
   Uniprot P19793 227-458

8. Domain d2p1va1: 2p1v A:229-458 [149167]
   automatically matched to d1lbda_
   complexed with 5tn

Details for d2p1va1

PDB Entry: 2p1v, 2.2 Å

PDB Description: Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-propoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2

PDB Compounds: (A:) Retinoic acid receptor RXR-alpha

SCOP Domain Sequences for d2p1va1:

Sequence, based on SEQRES records:

>d2p1va1 a.123.1.1 (A:229-458) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
dmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakriph
fselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdr
vltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhky
peqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d2p1va1 a.123.1.1 (A:229-458) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
dmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillragwne
lliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdktel
gclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalrs
iglkclehlfffkligdtpidtflmemleap

Timeline for d2p1va1:

• d2p1va1 is new in SCOP 1.75
  
• d2p1va1 is called d2p1va_ in SCOPe 2.01
  
• d2p1va1 appears in the current release, SCOPe 2.08, called d2p1va_