SCOPe 2.02: Domain d2opsa1: 2ops A:5-440

Lineage for d2opsa1 (2ops A:5-440)

1. Root: SCOPe 2.02

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [190022] (12 PDB entries)

8. Domain d2opsa1: 2ops A:5-440 [148968]
   automatically matched to d1c1cb_
   complexed with hbq, po4; mutant

Details for d2opsa1

PDB Entry: 2ops, 2.3 Å

PDB Description: crystal structure of y188c mutant hiv-1 reverse transcriptase in complex with gw420867x.

PDB Compounds: (A:) Reverse transcriptase/ribonuclease H

SCOPe Domain Sequences for d2opsa1:

Sequence, based on SEQRES records:

>d2opsa1 e.8.1.2 (A:5-440) HIV-1 reverse transcriptase {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlcvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyqlekepivgaetf

Sequence, based on observed residues (ATOM records):

>d2opsa1 e.8.1.2 (A:5-440) HIV-1 reverse transcriptase {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
wrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaf
tipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlcvg
sdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekd
swtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreil
kepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlte
avqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqle
kepivgaetf

Timeline for d2opsa1:

• d2opsa1 first appeared in SCOP 1.75
  
• d2opsa1 appears in SCOPe 2.01
  
• d2opsa1 does not appear in SCOPe 2.03