Lineage for d2j8ua2 (2j8u A:1-181)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
    dimeric
  4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families) (S)
  5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)
  6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (29 species)
  7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (104 PDB entries)
    Uniprot P01892 25-298
  8. Domain d2j8ua2: 2j8u A:1-181 [147918]
    Other proteins in same PDB: d2j8ua1, d2j8ub2, d2j8ub3, d2j8ue1, d2j8ue2, d2j8uf1, d2j8uf2, d2j8uh1, d2j8ui2, d2j8ui3, d2j8ul1, d2j8ul2, d2j8um1, d2j8um2
    automatically matched to d1akja2
    mutant

Details for d2j8ua2

PDB Entry: 2j8u (more details), 2.88 Å

PDB Description: large cdr3a loop alteration as a function of mhc mutation.
PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain

SCOPe Domain Sequences for d2j8ua2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2j8ua2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetravkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
r

SCOPe Domain Coordinates for d2j8ua2 are not available.

Timeline for d2j8ua2:

Domains from same chain:
(mouse over for more information)
d2j8ua1
Domains from other chains:
(mouse over for more information)
d2j8ub2, d2j8ub3, d2j8ue1, d2j8ue2, d2j8uf1, d2j8uf2, d2j8uh1, d2j8uh2, d2j8ui2, d2j8ui3, d2j8ul1, d2j8ul2, d2j8um1, d2j8um2