SCOP 1.75: Domain d2j8ua1: 2j8u A:182-275

Lineage for d2j8ua1 (2j8u A:182-275)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class I MHC, alpha-3 domain [88604] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88605] (157 PDB entries)
   Uniprot P30685 25-300
   Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor
   Uniprot P30481 25-300
   Uniprot P01892 25-298
   Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor
   Uniprot P30685 25-300 ! Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor ! Uniprot P30481 25-300 ! Uniprot P01892 25-298 ! Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor

8. Domain d2j8ua1: 2j8u A:182-275 [147917]
   Other proteins in same PDB: d2j8ua2, d2j8ub1, d2j8ue1, d2j8ue2, d2j8uf1, d2j8uf2, d2j8uh2, d2j8ui1, d2j8ul1, d2j8ul2, d2j8um1, d2j8um2
   automatically matched to d1akja1
   mutant

Details for d2j8ua1

PDB Entry: 2j8u, 2.88 Å

PDB Description: large cdr3a loop alteration as a function of mhc mutation.

PDB Compounds: (A:) HLA class I histocompatibility antigen, A-2 alpha chain

SCOP Domain Sequences for d2j8ua1:

Sequence; same for both SEQRES and ATOM records:

>d2j8ua1 b.1.1.2 (A:182-275) Class I MHC, alpha-3 domain {Human (Homo sapiens) [TaxId: 9606]}
tdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgtf
qkwaavvvpsgqeqrytchvqheglpkpltlrwe

Timeline for d2j8ua1:

• d2j8ua1 is new in SCOP 1.75
  
• d2j8ua1 appears in SCOPe 2.01
  
• d2j8ua1 appears in the current release, SCOPe 2.08