SCOPe 2.01: Domain d2hvca_: 2hvc A:

Lineage for d2hvca_ (2hvc A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (46 PDB entries)
   Uniprot P10275 671-919

8. Domain d2hvca_: 2hvc A: [147418]
   automated match to d1e3ga_
   protein/DNA complex; complexed with lgd

Details for d2hvca_

PDB Entry: 2hvc, 2.1 Å

PDB Description: The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2hvca_:

Sequence; same for both SEQRES and ATOM records:

>d2hvca_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
cqpiflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnl
hvddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmr
hlsqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrkn
ptscsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkils
gkvkpiyfht

Timeline for d2hvca_:

• d2hvca_ first appeared in SCOP 1.75, called d2hvca1
  
• d2hvca_ appears in SCOPe 2.02
  
• d2hvca_ appears in the current release, SCOPe 2.08