SCOPe 2.07: Domain d2ei8b_: 2ei8 B:

Lineage for d2ei8b_ (2ei8 B:)

1. Root: SCOPe 2.07

2. Class g: Small proteins [56992] (98 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (85 PDB entries)
   Uniprot P00742 127-178

8. Domain d2ei8b_: 2ei8 B: [146867]
   Other proteins in same PDB: d2ei8a_
   automated match to d1g2lb_
   complexed with ca, dt8

Details for d2ei8b_

PDB Entry: 2ei8, 2.1 Å

PDB Description: factor xa in complex with the inhibitor (1s,2r,4s)-n1-[(5-chloroindol-2-yl)carbonyl]-4-(n,n-dimethylcarbamoyl)-n2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine

PDB Compounds: (B:) coagulation factor x, light chain

SCOPe Domain Sequences for d2ei8b_:

Sequence; same for both SEQRES and ATOM records:

>d2ei8b_ g.3.11.1 (B:) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
trklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d2ei8b_:

• d2ei8b_ first appeared in SCOP 1.75, called d2ei8b1
  
• d2ei8b_ appears in SCOPe 2.06
  
• d2ei8b_ appears in the current release, SCOPe 2.08