SCOP 1.75: Domain d2z0ea1: 2z0e A:5-354

Lineage for d2z0ea1 (2z0e A:5-354)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (22 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.22: Autophagin-like [159858] (2 proteins)
   Pfam PF03416

6. Protein Cysteine protease ATG4B [159861] (1 species)
   Autophagin-1

7. Species Human (Homo sapiens) [TaxId:9606] [159862] (4 PDB entries)
   Uniprot Q9Y4P1 10-373! Uniprot Q9Y4P1 5-354

8. Domain d2z0ea1: 2z0e A:5-354 [145770]
   Other proteins in same PDB: d2z0eb1
   automatically matched to 2Z0D A:5-354
   mutant

Details for d2z0ea1

PDB Entry: 2z0e, 1.9 Å

PDB Description: the crystal structure of human atg4b- lc3(1-124) complex

PDB Compounds: (A:) Cysteine protease ATG4B

SCOP Domain Sequences for d2z0ea1:

Sequence, based on SEQRES records:

>d2z0ea1 d.3.1.22 (A:5-354) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tsvpcagatafpadsdrhcngfpagaevtnrpspwrplvlliplrlgltdineayvetlk
hcfmmpqslgviggkpnsahyfigyvgeeliyldpattqpaveptdgcfipdesfhcqhp
pcrmsiaeldpsiavgffckteddfndwcqqvkklsllggalpmfelveq

Sequence, based on observed residues (ATOM records):

>d2z0ea1 d.3.1.22 (A:5-354) Cysteine protease ATG4B {Human (Homo sapiens) [TaxId: 9606]}
tltydtlrfaefedfpetsepvwilgrkysiftekdeilsdvasrlwftyrknfpaiggt
gptsdtgwgcmlrcgqmifaqalvcrhlgrdwrwtqrkrqpdsyfsvlnafidrkdsyys
ihqiaqmgvgegksigqwygpntvaqvlkklavfdtwsslavhiamdntvvmeeirrlcr
tspwrplvlliplrlgltdineayvetlkhcfmmpqslgviggkpnsahyfigyvgeeli
yldpattqpavepipdesfhcqhppcrmsiaeldpsiavgffckteddfndwcqqvkkls
llggalpmfelveq

Timeline for d2z0ea1:

• d2z0ea1 is new in SCOP 1.75
  
• d2z0ea1 is called d2z0ea_ in SCOPe 2.01
  
• d2z0ea1 appears in the current release, SCOPe 2.08, called d2z0ea_