SCOPe 2.03: Domain d2ot3b1: 2ot3 B:17-182

Lineage for d2ot3b1 (2ot3 B:17-182)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab21 [142285] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142286] (3 PDB entries)
   Uniprot Q9UL25 16-182

8. Domain d2ot3b1: 2ot3 B:17-182 [145726]
   Other proteins in same PDB: d2ot3a_

Details for d2ot3b1

PDB Entry: 2ot3, 2.1 Å

PDB Description: crystal structure of rabex-5 vps9 domain in complex with nucleotide free rab21

PDB Compounds: (B:) Ras-related protein Rab-21

SCOPe Domain Sequences for d2ot3b1:

Sequence, based on SEQRES records:

>d2ot3b1 c.37.1.8 (B:17-182) Rab21 {Human (Homo sapiens) [TaxId: 9606]}
aysfkvvllgegcvgktslvlrycenkfndkhittlqasfltkklniggkrvnlaiwdta
gqerfhalgpiyyrdsngailvyditdedsfqkvknwvkelrkmlgneiclcivgnkidl
ekerhvsiqeaesyaesvgakhyhtsakqnkgieelfldlckrmie

Sequence, based on observed residues (ATOM records):

>d2ot3b1 c.37.1.8 (B:17-182) Rab21 {Human (Homo sapiens) [TaxId: 9606]}
aysfkvvllgegcvgktslvlrycttlqasfltkklniggkrvnlaiwdtagqerfhalg
piyyrdsngailvyditdedsfqkvknwvkelrkmlgneiclcivgnkidlekerhvsiq
eaesyaesvgakhyhtsakqnkgieelfldlckrmie

Timeline for d2ot3b1:

• d2ot3b1 first appeared in SCOP 1.75
  
• d2ot3b1 appears in SCOPe 2.02
  
• d2ot3b1 appears in SCOPe 2.04
  
• d2ot3b1 appears in the current release, SCOPe 2.08