SCOPe 2.06: Domain d2gd4c1: 2gd4 C:4-431

Lineage for d2gd4c1 (2gd4 C:4-431)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (27 PDB entries)
   Uniprot P01008

8. Domain d2gd4c1: 2gd4 C:4-431 [145193]
   Other proteins in same PDB: d2gd4a1, d2gd4b1, d2gd4h1, d2gd4l1
   complexed with ca, nag, nto

Details for d2gd4c1

PDB Entry: 2gd4, 3.3 Å

PDB Description: crystal structure of the antithrombin-s195a factor xa-pentasaccharide complex

PDB Compounds: (C:) antithrombin-III

SCOPe Domain Sequences for d2gd4c1:

Sequence, based on SEQRES records:

>d2gd4c1 e.1.1.1 (C:4-431) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
pvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfy
qhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfff
aklncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsr
aainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykad
gescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpev
lqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspaasalpgivaegrddly
vsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifm
grvanpcv

Sequence, based on observed residues (ATOM records):

>d2gd4c1 e.1.1.1 (C:4-431) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
pvdictakprdipmnpmciyrspeqkipeatnrrvwelskansrfattfyqhladskndn
dniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrk
ankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
tegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmy
qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
mmlvvhmprfriedgfslkeqlqdmglvdlfspaasalpgivaegrddlyvsdafhkafl
evneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv

Timeline for d2gd4c1:

• d2gd4c1 first appeared in SCOP 1.75
  
• d2gd4c1 appears in SCOPe 2.05
  
• d2gd4c1 appears in SCOPe 2.07
  
• d2gd4c1 appears in the current release, SCOPe 2.08