SCOPe 2.06: Domain d2ez0b1: 2ez0 B:18-458

Lineage for d2ez0b1 (2ez0 B:18-458)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.20: Clc chloride channel [81341] (1 superfamily)
   core: 18 transmembrane helices

4. Superfamily f.20.1: Clc chloride channel [81340] (1 family)

5. Family f.20.1.1: Clc chloride channel [69912] (2 proteins)
   duplication: consist of two similar structural parts

6. Protein Clc chloride channel [69913] (2 species)

7. Species Escherichia coli [TaxId:562] [69914] (18 PDB entries)

8. Domain d2ez0b1: 2ez0 B:18-458 [145129]
   Other proteins in same PDB: d2ez0d1, d2ez0d2, d2ez0f1, d2ez0f2
   automatically matched to 2EZ0 A:17-460
   complexed with br; mutant

Details for d2ez0b1

PDB Entry: 2ez0, 3.54 Å

PDB Description: crystal structure of the s107a/e148q/y445a mutant of ecclc, in complex with a fab fragment

PDB Compounds: (B:) H(+)/Cl(-) exchange transporter clcA

SCOPe Domain Sequences for d2ez0b1:

Sequence; same for both SEQRES and ATOM records:

>d2ez0b1 f.20.1.1 (B:18-458) Clc chloride channel {Escherichia coli [TaxId: 562]}
rrqlirqllerdktplailfmaavvgtlvglaavafdkgvawlqnqrmgalvhtadnypl
lltvaflcsavlamfgyflvrkyapeaggagipeiegaledqrpvrwwrvlpvkffgglg
tlgggmvlgrqgptvqiggnigrmvldifrlkgdearhtllatgaaaglaaafnaplagi
lfiieemrpqfrytlisikavfigvimstimyrifnhevalidvgklsdaplntlwlyli
lgiifgifgpifnkwvlgmqdllhrvhggnitkwvlmggaigglcgllgfvapatsgggf
nlipiatagnfsmgmlvfifvarvittllcfssgapggifapmlalgtvlgtafgmvave
lfpqyhleagtfaiagmgallaasirapltgiilvlemtdnyqlilpmiitglgatllaq
ftggkplasailartlakqea

Timeline for d2ez0b1:

• d2ez0b1 first appeared in SCOP 1.75
  
• d2ez0b1 appears in SCOPe 2.05
  
• d2ez0b1 appears in SCOPe 2.07
  
• d2ez0b1 appears in the current release, SCOPe 2.08