SCOPe 2.07: Domain d1yyls1: 1yyl S:1002-1027

Lineage for d1yyls1 (1yyl S:1002-1027)

1. Root: SCOPe 2.07

2. Class k: Designed proteins [58788] (44 folds)

3. Fold k.23: Scorpion toxin-based designs [58917] (1 superfamily)

4. Superfamily k.23.1: Scorpion toxin-based designs [58918] (2 families)

5. Family k.23.1.2: Mini-protein reproducing the core of the CD4 surface [58922] (1 protein)

6. Protein Mini-protein reproducing the core of the CD4 surface [58923] (1 species)
   interacting with the hiv-1 envelope glycoprotein

7. Species Synthetic [58924] (5 PDB entries)

8. Domain d1yyls1: 1yyl S:1002-1027 [144722]
   Other proteins in same PDB: d1yylg_, d1yylh1, d1yylh2, d1yyll1, d1yyll2, d1yylp_, d1yylq1, d1yylq2, d1yylr1, d1yylr2
   automatically matched to 1YYL M:2-27
   complexed with nag, ndg

Details for d1yyls1

PDB Entry: 1yyl, 2.75 Å

PDB Description: crystal structure of cd4m33, a scorpion-toxin mimic of cd4, in complex with hiv-1 yu2 gp120 envelope glycoprotein and anti-hiv-1 antibody 17b

PDB Compounds: (S:) CD4M33, scorpion-toxin mimic of CD4

SCOPe Domain Sequences for d1yyls1:

Sequence; same for both SEQRES and ATOM records:

>d1yyls1 k.23.1.2 (S:1002-1027) Mini-protein reproducing the core of the CD4 surface {Synthetic}
nlhfcqlrckslgllgkcagsfcacx

Timeline for d1yyls1:

• d1yyls1 first appeared in SCOP 1.75
  
• d1yyls1 appears in SCOPe 2.06
  
• d1yyls1 appears in the current release, SCOPe 2.08