SCOP 1.73: Protein: Presequence protease 1, PREP1

Lineage for Protein: Presequence protease 1, PREP1

Root: SCOP 1.73
Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily)
core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta
Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (2 families)
Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues

Family d.185.1.1: MPP-like [63412] (6 proteins)
Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal

Protein Presequence protease 1, PREP1 [143498] (1 species)
duplication: comprises four domains of this fold; similar to the MPP alpha-beta heterodimer

Species:

Thale cress (Arabidopsis thaliana) [TaxId:3702] [143499] (1 PDB entry)
- Domains for 2fge:
  1. Domain d2fgea1: 2fge A:540-797 [133430]
    complexed with cl, mg, zn; mutant
  2. Domain d2fgea2: 2fge A:798-993 [133431]
    complexed with cl, mg, zn; mutant
  3. Domain d2fgea3: 2fge A:272-539 [133432]
    complexed with cl, mg, zn; mutant
  4. Domain d2fgea4: 2fge A:15-271 [133433]
    complexed with cl, mg, zn; mutant
  5. Domain d2fgeb1: 2fge B:540-797 [133434]
    automatically matched to 2FGE A:540-797
    complexed with cl, mg, zn; mutant
  6. Domain d2fgeb2: 2fge B:798-993 [133435]
    automatically matched to 2FGE A:798-993
    complexed with cl, mg, zn; mutant
  7. Domain d2fgeb3: 2fge B:272-539 [133436]
    automatically matched to 2FGE A:272-539
    complexed with cl, mg, zn; mutant
  8. Domain d2fgeb4: 2fge B:15-271 [133437]
    automatically matched to 2FGE A:15-271
    complexed with cl, mg, zn; mutant

More info for Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like

Timeline for Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like:

Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like is new in SCOP 1.73
Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like appears in SCOP 1.75
Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like appears in the current release, SCOPe 2.08