Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.185: LuxS/MPP-like metallohydrolase [63410] (1 superfamily) core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta |
Superfamily d.185.1: LuxS/MPP-like metallohydrolase [63411] (3 families) Share the same "active site motif" HxxEH located in the first core helix, but differ in one of the zinc-binding residues |
Family d.185.1.1: MPP-like [63412] (7 proteins) Common fold elaborated with many additional structures; duplication: each family member consists of two similar domains of beta(2)-alpha(2)-beta(2)-alpha(5)-beta structure, but only the N-terminal domain of MPP beta chain binds the catalytic metal |
Protein Presequence protease 1, PREP1 [143498] (1 species) duplication: comprises four domains of this fold; similar to the MPP alpha-beta heterodimer |
Thale cress (Arabidopsis thaliana) [TaxId:3702] [143499] (1 PDB entry) Uniprot Q9LJL3 100-356! Uniprot Q9LJL3 357-624! Uniprot Q9LJL3 625-882! Uniprot Q9LJL3 883-1078 |
Domain d2fgea1: 2fge A:540-797 [133430] complexed with cl, mg, zn |
Domain d2fgea2: 2fge A:798-993 [133431] complexed with cl, mg, zn |
Domain d2fgea3: 2fge A:272-539 [133432] complexed with cl, mg, zn |
Domain d2fgea4: 2fge A:15-271 [133433] complexed with cl, mg, zn |
Domain d2fgeb1: 2fge B:540-797 [133434] automated match to d2fgea1 complexed with cl, mg, zn |
Domain d2fgeb2: 2fge B:798-993 [133435] automated match to d2fgea2 complexed with cl, mg, zn |
Domain d2fgeb3: 2fge B:272-539 [133436] automated match to d2fgea3 complexed with cl, mg, zn |
Domain d2fgeb4: 2fge B:15-271 [133437] automated match to d2fgea4 complexed with cl, mg, zn |
Timeline for Protein Presequence protease 1, PREP1 from d.185.1.1: MPP-like: