SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: Kinetochore protein Spc24

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2215948Fold d.300: Kinetochore globular domain-like [143025] (1 superfamily)
    core: alpha-beta(3)-alpha; variant: alpha-beta(4)-alpha(2)
  4. 2215949Superfamily d.300.1: Kinetochore globular domain [143026] (2 families) (S)
    swapped heterodimer with the N-terminal helices; Spc24-like subunits have the core fold, whereas Spc25-like subunits have a variant fold
  5. 2215955Family d.300.1.2: Spc24-like [143030] (1 protein)
    Pfam PF08286
  6. 2215956Protein Kinetochore protein Spc24 [143031] (2 species)


  1. 2215957Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [143032] (2 PDB entries)
    Uniprot Q04477 155-213! Uniprot Q04477 156-213
    1. Domain for 2ftx:
    2. Domain for 2fv4:
  2. 2282771Saccharomyces cerevisiae [TaxId:559292] [326072] (1 PDB entry)

More info for Protein Kinetochore protein Spc24 from d.300.1.2: Spc24-like

Timeline for Protein Kinetochore protein Spc24 from d.300.1.2: Spc24-like: