Lineage for Species: Saccharopolyspora erythraea [TaxId: 1836]

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2449371Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2449372Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2449736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2450770Protein Erythromycin synthase, eryAI, 1st ketoreductase module [141909] (1 species)
    tandem repeat of two SDR-like modules resembling a dimer commonly founf in the family; only the second module retains the coenzyme-binding site
  7. 2450771Species Saccharopolyspora erythraea [TaxId:1836] [141910] (4 PDB entries)
    Uniprot Q5UNP6 1448-1656! Uniprot Q5UNP6 1657-1915

PDB entries in Species: Saccharopolyspora erythraea [TaxId: 1836]:

  1. Domain(s) for 2fr0:
    1. 2450774Domain d2fr0a1: 2fr0 A:1657-1915 [133959]
      complexed with ndp
    2. 2450775Domain d2fr0a2: 2fr0 A:1448-1656 [133960]
      complexed with ndp
  2. Domain(s) for 2fr1:
    1. 2450772Domain d2fr1a1: 2fr1 A:1657-1915 [133961]
      automated match to d2fr0a1
      complexed with ndp
    2. 2450773Domain d2fr1a2: 2fr1 A:1448-1656 [133962]
      automated match to d2fr0a2
      complexed with ndp
  3. Domain(s) for 6w7s:
    1. 2450776Domain d6w7sa1: 6w7s A:1448-1654 [392914]
      Other proteins in same PDB: d6w7sl1, d6w7sl2
      automated match to d2fr1a2
      complexed with cl, mes
    2. 2450777Domain d6w7sa2: 6w7s A:1659-1914 [392915]
      Other proteins in same PDB: d6w7sl1, d6w7sl2
      automated match to d2fr1a1
      complexed with cl, mes
  4. Domain(s) for 6wh9:
    1. 2450778Domain d6wh9a1: 6wh9 A:1448-1653 [392952]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a2
      complexed with so4
    2. 2450779Domain d6wh9a2: 6wh9 A:1664-1909 [392953]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a1
      complexed with so4
    3. 2450780Domain d6wh9d1: 6wh9 D:1448-1655 [392959]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a2
      complexed with so4
    4. 2450781Domain d6wh9d2: 6wh9 D:1659-1910 [392960]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a1
      complexed with so4
    5. 2450782Domain d6wh9g1: 6wh9 G:1448-1655 [392955]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a2
      complexed with so4
    6. 2450783Domain d6wh9g2: 6wh9 G:1662-1910 [392956]
      Other proteins in same PDB: d6wh9c1, d6wh9c2, d6wh9d3, d6wh9f1, d6wh9f2, d6wh9i1, d6wh9i2
      automated match to d2fr1a1
      complexed with so4

More info for Species Saccharopolyspora erythraea [TaxId:1836] from c.2.1.2 Erythromycin synthase, eryAI, 1st ketoreductase module

Timeline for Species Saccharopolyspora erythraea [TaxId:1836] from c.2.1.2 Erythromycin synthase, eryAI, 1st ketoreductase module:

  • Species Saccharopolyspora erythraea [TaxId:1836] from c.2.1.2 Erythromycin synthase, eryAI, 1st ketoreductase module first appeared in SCOP 1.73
  • Species Saccharopolyspora erythraea [TaxId:1836] from c.2.1.2 Erythromycin synthase, eryAI, 1st ketoreductase module appears in SCOPe 2.06
  • Species Saccharopolyspora erythraea [TaxId:1836] from c.2.1.2 Erythromycin synthase, eryAI, 1st ketoreductase module does not appear in SCOPe 2.08