Lineage for Species: Mouse (Mus musculus) [TaxId: 10090]

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 819418Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 819419Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 819736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 819766Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (3 species)
  7. 819817Species Mouse (Mus musculus) [TaxId:10090] [141879] (2 PDB entries)
    Uniprot P50172 24-298

PDB entries in Species: Mouse (Mus musculus) [TaxId: 10090]:

  1. Domain(s) for 1y5m:
    1. 819818Domain d1y5ma1: 1y5m A:25-289 [122645]
      complexed with ndp, oct, so4
    2. 819819Domain d1y5mb1: 1y5m B:25-289 [122646]
      automatically matched to 1Y5M A:25-289
      complexed with ndp, oct, so4
  2. Domain(s) for 1y5r:
    1. 819820Domain d1y5ra1: 1y5r A:25-289 [122651]
      automatically matched to 1Y5M A:25-289
      complexed with c0r, ndp
    2. 819821Domain d1y5rb1: 1y5r B:25-289 [122652]
      automatically matched to 1Y5M A:25-289
      complexed with c0r, ndp

More info for Species Mouse (Mus musculus) [TaxId:10090] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1

Timeline for Species Mouse (Mus musculus) [TaxId:10090] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1: