Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
    has additional subdomain(s) that are not in the common domain
  6. 2842760Protein Sepiapterin reductase [51767] (2 species)
  7. 2842761Species Human (Homo sapiens) [TaxId:9606] [141874] (14 PDB entries)
    Uniprot P35270 5-261

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1z6z:
    1. 2842796Domain d1z6za1: 1z6z A:2-258 [124575]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      complexed with cl, nap, so4
    2. 2842797Domain d1z6zb2: 1z6z B:2-258 [124576]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      automated match to d1z6za1
      complexed with cl, nap, so4
    3. 2842798Domain d1z6zc2: 1z6z C:2-258 [124577]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      automated match to d1z6za1
      complexed with cl, nap, so4
    4. 2842799Domain d1z6zd2: 1z6z D:2-258 [124578]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      automated match to d1z6za1
      complexed with cl, nap, so4
    5. 2842800Domain d1z6ze2: 1z6z E:2-258 [124579]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      automated match to d1z6za1
      complexed with cl, nap, so4
    6. 2842801Domain d1z6zf2: 1z6z F:2-258 [124580]
      Other proteins in same PDB: d1z6za2, d1z6zb3, d1z6zc3, d1z6zd3, d1z6ze3, d1z6zf3
      automated match to d1z6za1
      complexed with cl, nap, so4
  2. Domain(s) for 4hwk:
    1. 2842774Domain d4hwka_: 4hwk A: [252530]
      automated match to d1z6za1
      complexed with gol, nap, peg, sfy, so4
    2. 2842775Domain d4hwkb_: 4hwk B: [252531]
      automated match to d1z6za1
      complexed with gol, nap, peg, sfy, so4
    3. 2842776Domain d4hwkc_: 4hwk C: [252532]
      automated match to d1z6za1
      complexed with gol, nap, peg, sfy, so4
    4. 2842777Domain d4hwkd_: 4hwk D: [252533]
      automated match to d1z6za1
      complexed with gol, nap, peg, sfy, so4
  3. Domain(s) for 4j7u:
    1. 2842778Domain d4j7ua_: 4j7u A: [252835]
      automated match to d1z6za1
      complexed with gol, nap, peg, so4, ytz
    2. 2842779Domain d4j7ub_: 4j7u B: [252836]
      automated match to d1z6za1
      complexed with gol, nap, peg, so4, ytz
    3. 2842780Domain d4j7uc_: 4j7u C: [252837]
      automated match to d1z6za1
      complexed with gol, nap, peg, so4, ytz
    4. 2842781Domain d4j7ud_: 4j7u D: [252838]
      automated match to d1z6za1
      complexed with gol, nap, peg, so4, ytz
  4. Domain(s) for 4j7x:
    1. 2842792Domain d4j7xa_: 4j7x A: [252839]
      automated match to d1z6za1
      complexed with gol, nap, peg, sas, so4
    2. 2842793Domain d4j7xb_: 4j7x B: [252840]
      automated match to d1z6za1
      complexed with gol, nap, peg, sas, so4
    3. 2842794Domain d4j7xf_: 4j7x F: [252841]
      automated match to d1z6za1
      complexed with gol, nap, peg, sas, so4
    4. 2842795Domain d4j7xj_: 4j7x J: [252842]
      automated match to d1z6za1
      complexed with gol, nap, peg, sas, so4
  5. Domain(s) for 4xwy:
    1. 2842788Domain d4xwya_: 4xwy A: [274553]
      automated match to d1z6zb_
      complexed with 43o, ndp, so4
    2. 2842789Domain d4xwyb_: 4xwy B: [274554]
      automated match to d1z6zb_
      complexed with 43o, ndp, so4
    3. 2842790Domain d4xwyc_: 4xwy C: [274555]
      automated match to d1z6zb_
      complexed with 43o, ndp, so4
    4. 2842791Domain d4xwyd_: 4xwy D: [274556]
      automated match to d1z6zb_
      complexed with 43o, ndp, so4
  6. Domain(s) for 4z3k:
    1. 2842784Domain d4z3ka_: 4z3k A: [279521]
      automated match to d1z6zb_
      complexed with 4kl, edo, nap, so4
    2. 2842785Domain d4z3kb_: 4z3k B: [279520]
      automated match to d1z6zb_
      complexed with 4kl, edo, nap, so4
    3. 2842786Domain d4z3kc_: 4z3k C: [279518]
      automated match to d1z6zb_
      complexed with 4kl, edo, nap, so4
    4. 2842787Domain d4z3kd_: 4z3k D: [279519]
      automated match to d1z6zb_
      complexed with 4kl, edo, nap, so4
  7. Domain(s) for 6i6c:
    1. 2842770Domain d6i6ca1: 6i6c A:1-260 [370262]
      Other proteins in same PDB: d6i6ca2
      automated match to d4hwka_
      complexed with edo, h4h, nap
    2. 2842771Domain d6i6cb_: 6i6c B: [370244]
      Other proteins in same PDB: d6i6ca2
      automated match to d4hwka_
      complexed with edo, h4h, nap
  8. Domain(s) for 6i6f:
    1. 2842782Domain d6i6fa1: 6i6f A:1-260 [370224]
      Other proteins in same PDB: d6i6fa2
      automated match to d4hwka_
      complexed with edo, h4e, nap
    2. 2842783Domain d6i6fb_: 6i6f B: [370260]
      Other proteins in same PDB: d6i6fa2
      automated match to d4hwka_
      complexed with edo, h4e, nap
  9. Domain(s) for 6i6p:
    1. 2842766Domain d6i6pa1: 6i6p A:1-261 [370239]
      Other proteins in same PDB: d6i6pa2
      automated match to d4hwka_
      complexed with edo, h4t, nap
    2. 2842767Domain d6i6pb_: 6i6p B: [370270]
      Other proteins in same PDB: d6i6pa2
      automated match to d4hwka_
      complexed with edo, h4t, nap
  10. Domain(s) for 6i6t:
    1. 2842772Domain d6i6ta_: 6i6t A: [370261]
      automated match to d4hwka_
      complexed with edo, h5b, nap
    2. 2842773Domain d6i6tb_: 6i6t B: [370193]
      automated match to d4hwka_
      complexed with edo, h5b, nap
  11. Domain(s) for 6i6v:
    1. 2842762Domain d6i6va1: 6i6v A:1-260 [370204]
      Other proteins in same PDB: d6i6va2
      automated match to d4hwka_
      complexed with edo, h6e, nap
    2. 2842763Domain d6i6vb_: 6i6v B: [370191]
      Other proteins in same PDB: d6i6va2
      automated match to d4hwka_
      complexed with edo, h6e, nap
  12. Domain(s) for 6i79:
    1. 2842768Domain d6i79a1: 6i79 A:1-261 [370254]
      Other proteins in same PDB: d6i79a2, d6i79b2
      automated match to d4hwka_
      complexed with h5e, nap
    2. 2842769Domain d6i79b1: 6i79 B:1-261 [370281]
      Other proteins in same PDB: d6i79a2, d6i79b2
      automated match to d4hwka_
      complexed with h5e, nap
  13. Domain(s) for 6usn:
    1. 2842802Domain d6usna_: 6usn A: [378166]
      automated match to d4hwka_
      complexed with gol, nap, peg, qgv, so4
    2. 2842803Domain d6usnb_: 6usn B: [378155]
      automated match to d4hwka_
      complexed with gol, nap, peg, qgv, so4
    3. 2842804Domain d6usnc_: 6usn C: [378145]
      automated match to d4hwka_
      complexed with gol, nap, peg, qgv, so4
    4. 2842805Domain d6usnd_: 6usn D: [378146]
      automated match to d4hwka_
      complexed with gol, nap, peg, qgv, so4
  14. Domain(s) for 7dsf:
    1. 2842764Domain d7dsfa_: 7dsf A: [398920]
      automated match to d4hwka_
      complexed with act, nap, zn
    2. 2842765Domain d7dsfb_: 7dsf B: [398955]
      automated match to d4hwka_
      complexed with act, nap, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 Sepiapterin reductase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 Sepiapterin reductase: