SCOPe 2.06: Domain d2p8yt2: 2p8y T:3-343

Lineage for d2p8yt2 (2p8y T:3-343)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Elongation factor 2 (eEF-2), N-terminal (G) domain [82404] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82405] (13 PDB entries)
   Uniprot P32324

8. Domain d2p8yt2: 2p8y T:3-343 [139547]
   Other proteins in same PDB: d2p8yt1, d2p8yt3, d2p8yt4, d2p8yt5
   automatically matched to d1n0vc2
   complexed with apr, gdp, so1

Details for d2p8yt2

PDB Entry: 2p8y, 11.7 Å

PDB Description: fitted structure of adpr-eef2 in the 80s:adpr-eef2:gdp:sordarin cryo- em reconstruction

PDB Compounds: (T:) Elongation factor 2

SCOPe Domain Sequences for d2p8yt2:

Sequence, based on SEQRES records:

>d2p8yt2 c.37.1.8 (T:3-343) Elongation factor 2 (eEF-2), N-terminal (G) domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
aftvdqmrslmdkvtnvrnmsviahvdhgkstltdslvqragiisaakagearftdtrkd
eqergitikstaislysemsdedvkeikqktdgnsflinlidspghvdfssevtaalrvt
dgalvvvdtiegvcvqtetvlrqalgerikpvvvinkvdrallelqvskedlyqtfartv
esvnvivstyadevlgdvqvypargtvafgsglhgwaftirqfatryakkfgvdkakmmd
rlwgdsffnpktkkwtnkdtdaegkplerafnmfildpifrlftaimnfkkdeipvllek
leivlkgdekdlegkallkvvmrkflpaadallemivlhlp

Sequence, based on observed residues (ATOM records):

>d2p8yt2 c.37.1.8 (T:3-343) Elongation factor 2 (eEF-2), N-terminal (G) domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
aftvdqmrslmdkvtnvrnmsviahvdhgkstltdslvqragiisagitikstaislyse
msdedvkeikqktdgnsflinlidspghvdfssevtaalrvtdgalvvvdtiegvcvqte
tvlrqalgerikpvvvinkvdrallelqvskedlyqtfartvesvnvivstyadevlgdv
qvypargtvafgsglhgwaftirqfatryakkfgvdkakmmdrlwgdsffnpktkkwtnk
dtdaegkplerafnmfildpifrlftaimnfkkdeipvllekleivlkgdekdlegkall
kvvmrkflpaadallemivlhlp

Timeline for d2p8yt2:

• d2p8yt2 first appeared in SCOP 1.73
  
• d2p8yt2 appears in SCOPe 2.05
  
• d2p8yt2 appears in SCOPe 2.07
  
• d2p8yt2 appears in the current release, SCOPe 2.08