SCOP 1.73: Domain d2oj9a1: 2oj9 A:954-1256

Lineage for d2oj9a1 (2oj9 A:954-1256)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (5 PDB entries)

8. Domain d2oj9a1: 2oj9 A:954-1256 [139102]
   automatically matched to d1m7na_
   complexed with bmi

Details for d2oj9a1

PDB Entry: 2oj9, 2 Å

PDB Description: Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor

PDB Compounds: (A:) Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen)

SCOP Domain Sequences for d2oj9a1:

Sequence, based on SEQRES records:

>d2oj9a1 d.144.1.7 (A:954-1256) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
advyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmre
rieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpv
lappslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyet
dyyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlr
fvmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyse
enk

Sequence, based on observed residues (ATOM records):

>d2oj9a1 d.144.1.7 (A:954-1256) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
advyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmre
rieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpeppslsk
miqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggk
gllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmeggll
dkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

Timeline for d2oj9a1:

• d2oj9a1 is new in SCOP 1.73
  
• d2oj9a1 appears in SCOP 1.75
  
• d2oj9a1 appears in the current release, SCOPe 2.08, called d2oj9a_