Lineage for d2ny5h2 (2ny5 H:3129-3228)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 785070Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (7 species)
  7. 785078Species Human (Homo sapiens) [TaxId:9606] [88575] (172 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)
    SQ NA # humanized antibody
    Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region
    SQ NA # engineered antibody
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 785201Domain d2ny5h2: 2ny5 H:3129-3228 [138791]
    Other proteins in same PDB: d2ny5c1, d2ny5c2, d2ny5g1, d2ny5h1, d2ny5l1, d2ny5l2
    automatically matched to d1ngzb2
    complexed with nag, suc; mutant

Details for d2ny5h2

PDB Entry: 2ny5 (more details), 2.5 Å

PDB Description: hiv-1 gp120 envelope glycoprotein (m95w, w96c, i109c, t257s, v275c, s334a, s375w, q428c, a433m) complexed with cd4 and antibody 17b
PDB Compounds: (H:) antibody 17b, heavy chain

SCOP Domain Sequences for d2ny5h2:

Sequence, based on SEQRES records: (download)

>d2ny5h2 b.1.1.2 (H:3129-3228) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

Sequence, based on observed residues (ATOM records): (download)

>d2ny5h2 b.1.1.2 (H:3129-3228) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

SCOP Domain Coordinates for d2ny5h2:

Click to download the PDB-style file with coordinates for d2ny5h2.
(The format of our PDB-style files is described here.)

Timeline for d2ny5h2: