SCOPe 2.08: Domain d2j88l2: 2j88 L:109-205

Lineage for d2j88l2 (2j88 L:109-205)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (374 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d2j88l2: 2j88 L:109-205 [138138]
   Other proteins in same PDB: d2j88a_, d2j88h1, d2j88l1
   automatically matched to d1a0ql2

Details for d2j88l2

PDB Entry: 2j88, 2.6 Å

PDB Description: Hyaluronidase in complex with a monoclonal IgG Fab fragment

PDB Compounds: (L:) fab

SCOPe Domain Sequences for d2j88l2:

Sequence, based on SEQRES records:

>d2j88l2 b.1.1.2 (L:109-205) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqds
kdstysmsstltltkdeyerhnsytceathktstspi

Sequence, based on observed residues (ATOM records):

>d2j88l2 b.1.1.2 (L:109-205) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifvvcflnnfypkdinvkwkgvlnswtdqddstysmsstltltkdeytceat
hktstspi

Timeline for d2j88l2:

• d2j88l2 first appeared in SCOP 1.73
  
• d2j88l2 appears in SCOPe 2.07