SCOP 1.73: Domain d2j4wl1: 2j4w L:3-107

Lineage for d2j4wl1 (2j4w L:3-107)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88528] (40 PDB entries)

8. Domain d2j4wl1: 2j4w L:3-107 [138007]
   Other proteins in same PDB: d2j4wl2
   automatically matched to d1dqdl1
   mutant

Details for d2j4wl1

PDB Entry: 2j4w, 2.5 Å

PDB Description: structure of a plasmodium vivax apical membrane antigen 1-fab f8.12.19 complex

PDB Compounds: (L:) fab fragment of monoclonal antibody f8.12.19

SCOP Domain Sequences for d2j4wl1:

Sequence; same for both SEQRES and ATOM records:

>d2j4wl1 b.1.1.1 (L:3-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
vlsqspailsaspgekvtmtcrarssvsymhwyqqksgsspkpwihatsnlasgvparfs
gsgsgtsysltisrveaedaatyycqqwsshpptfgsgtkleik

Timeline for d2j4wl1:

• d2j4wl1 is new in SCOP 1.73
  
• d2j4wl1 appears in SCOP 1.75
  
• d2j4wl1 appears in the current release, SCOPe 2.08