SCOPe 2.08: Domain d2io8a1: 2io8 A:379-496

Lineage for d2io8a1 (2io8 A:379-496)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.30: PreATP-grasp domain [52439] (1 superfamily)
   3 layers: a/b/a; parallel or mixed beta-sheet of 4 to 6 strands
   possible rudiment form of Rossmann-fold domain

4. Superfamily c.30.1: PreATP-grasp domain [52440] (10 families)
   precedes the ATP-grasp domain common to all superfamily members, can contain a substrate-binding function

5. Family c.30.1.7: Glutathionylspermidine synthase substrate-binding domain-like [142119] (1 protein)
   central part of Pfam PF03738; GSP; overal similarity of the Pfam domain to the Eukaryotic glutathione synthetase

6. Protein Glutathionylspermidine synthase, synthetase domain [142120] (1 species)

7. Species Escherichia coli [TaxId:562] [142121] (5 PDB entries)
   Uniprot P0AES0 379-496

8. Domain d2io8a1: 2io8 A:379-496 [137549]
   Other proteins in same PDB: d2io8a2, d2io8a3, d2io8b2, d2io8b3
   automated match to d2io7a1
   complexed with adp, cys, mg

Details for d2io8a1

PDB Entry: 2io8, 2.1 Å

PDB Description: E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP

PDB Compounds: (A:) Bifunctional glutathionylspermidine synthetase/amidase

SCOPe Domain Sequences for d2io8a1:

Sequence, based on SEQRES records:

>d2io8a1 c.30.1.7 (A:379-496) Glutathionylspermidine synthase, synthetase domain {Escherichia coli [TaxId: 562]}
rpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelgwdaagqlidgegrlvncv
wktwawetafdqirevsdrefaavpirtghpqnevrlidvllrpevlvfeplwtvipg

Sequence, based on observed residues (ATOM records):

>d2io8a1 c.30.1.7 (A:379-496) Glutathionylspermidine synthase, synthetase domain {Escherichia coli [TaxId: 562]}
rpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelgwdaagqlidgegrlvncv
wktwawetafdqirevefaavpirtghpqnevrlidvllrpevlvfeplwtvipg

Timeline for d2io8a1:

• d2io8a1 first appeared in SCOP 1.73
  
• d2io8a1 appears in SCOPe 2.07