SCOPe 2.03: Domain d2imcb_: 2imc B:

Lineage for d2imcb_ (2imc B:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (23 PDB entries)
   Uniprot P10845 1-419

8. Domain d2imcb_: 2imc B: [137514]
   automated match to d1xtga_
   complexed with zn

Details for d2imcb_

PDB Entry: 2imc, 2 Å

PDB Description: clostridium botulinum neurotoxin serotype a light chain, residues 1- 424

PDB Compounds: (B:) Botulinum neurotoxin A light-chain

SCOPe Domain Sequences for d2imcb_:

Sequence, based on SEQRES records:

>d2imcb_ d.92.1.7 (B:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
ssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdt
ftnpeegdlnpppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmllts
ivrgipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfgh
evlnltrngygstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihagh
rlygiainpnrvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkf
kdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiyt
ednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinn
mnftkl

Sequence, based on observed residues (ATOM records):

>d2imcb_ d.92.1.7 (B:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
ssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdt
ftnpeegdlnpppqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivr
gipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevl
nltrngygstqyirfspdftfgfeeslevllgagkfatdpavtlahelihaghrlygiai
npnrvfvsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttaslq
ymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdk
avfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftkl

Timeline for d2imcb_:

• d2imcb_ first appeared in SCOP 1.73, called d2imcb1
  
• d2imcb_ was called d2imcb1 in SCOPe 2.02
  
• d2imcb_ appears in SCOPe 2.04
  
• d2imcb_ appears in the current release, SCOPe 2.07, called d2imcb2