SCOPe 2.05: Domain d2ilpb_: 2ilp B:

Lineage for d2ilpb_ (2ilp B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (26 PDB entries)
   Uniprot P10845 1-419

8. Domain d2ilpb_: 2ilp B: [137497]
   automated match to d1xtga_
   complexed with gb5, po4, zn

Details for d2ilpb_

PDB Entry: 2ilp, 1.9 Å

PDB Description: clostridium botulinum serotype a light chain inhibited by 4- chlorocinnamic hydroxamate

PDB Compounds: (B:) Botulinum neurotoxin A light-chain

SCOPe Domain Sequences for d2ilpb_:

Sequence, based on SEQRES records:

>d2ilpb_ d.92.1.7 (B:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
ssglvprgshmqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdt
ftnpeegdlnpppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmllts
ivrgipfwggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfgh
evlnltrngygstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihagh
rlygiainpnrvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkf
kdiastlnkaksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiyt
ednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinn
mnftklk

Sequence, based on observed residues (ATOM records):

>d2ilpb_ d.92.1.7 (B:) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
ssglvprgshmqfvnkqfnykdpvngvdiayikipgqmqpvkafkihnkiwviperdtft
npeegdlnpppvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfw
ggstidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrn
gygstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiain
pnrvflevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttasl
qymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfd
kavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklk

Timeline for d2ilpb_:

• d2ilpb_ first appeared in SCOP 1.73, called d2ilpb1
  
• d2ilpb_ appears in SCOPe 2.04
  
• d2ilpb_ is called d2ilpb2 in SCOPe 2.06
  
• d2ilpb_ appears in the current release, SCOPe 2.08, called d2ilpb2