SCOPe 2.01: Domain d2ie3a_: 2ie3 A:

Lineage for d2ie3a_ (2ie3 A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (24 families)

5. Family a.118.1.2: HEAT repeat [48385] (2 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48387] (10 PDB entries)

8. Domain d2ie3a_: 2ie3 A: [137290]
   Other proteins in same PDB: d2ie3c1
   automated match to d1b3ua_
   complexed with mn

Details for d2ie3a_

PDB Entry: 2ie3, 2.8 Å

PDB Description: Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins

PDB Compounds: (A:) Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform

SCOPe Domain Sequences for d2ie3a_:

Sequence; same for both SEQRES and ATOM records:

>d2ie3a_ a.118.1.2 (A:) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

Timeline for d2ie3a_:

• d2ie3a_ first appeared in SCOP 1.73, called d2ie3a1
  
• d2ie3a_ was called d2ie3a1 in SCOP 1.75
  
• d2ie3a_ appears in SCOPe 2.02
  
• d2ie3a_ appears in the current release, SCOPe 2.08