Lineage for d2ianq1 (2ian Q:93-190)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 783929Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 784902Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)
  7. 784910Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (39 PDB entries)
    Uniprot P04229 30-219
    probably orthologous to the mouse I-E group
  8. 784952Domain d2ianq1: 2ian Q:93-190 [137176]
    Other proteins in same PDB: d2iana1, d2iana2, d2ianb2, d2ianf1, d2ianf2, d2iang2, d2iank1, d2iank2, d2ianl2, d2ianp1, d2ianp2, d2ianq2
    automatically matched to d1d5xb1
    mutant

Details for d2ianq1

PDB Entry: 2ian (more details), 2.8 Å

PDB Description: Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
PDB Compounds: (Q:) HLA class II histocompatibility antigen, DRB1-1 beta chain

SCOP Domain Sequences for d2ianq1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ianq1 b.1.1.2 (Q:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypsktqplqhhnllvcsvsgfypgsievrwfrngqeekagvvstgliqngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewra

SCOP Domain Coordinates for d2ianq1:

Click to download the PDB-style file with coordinates for d2ianq1.
(The format of our PDB-style files is described here.)

Timeline for d2ianq1: