SCOP 1.75: Domain d2hara1: 2har A:119-423

Lineage for d2hara1 (2har A:119-423)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48529] (13 PDB entries)

8. Domain d2hara1: 2har A:119-423 [136293]
   automatically matched to d1ie9a_
   complexed with occ

Details for d2hara1

PDB Entry: 2har, 1.9 Å

PDB Description: crystal structure of vdr lbd in complex with 2 alpha-(3-hydroxy-1- propoxy) calcitriol

PDB Compounds: (A:) Vitamin D3 receptor

SCOP Domain Sequences for d2hara1:

Sequence, based on SEQRES records:

>d2hara1 a.123.1.1 (A:119-423) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
slrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlph
ladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcg
nqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqda
alieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqpe
csmkltplvlevfg

Sequence, based on observed residues (ATOM records):

>d2hara1 a.123.1.1 (A:119-423) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
slrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlph
ladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcg
nqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqda
alieaiqdrlsntlqtyircrhpgshllyakmiqkladlrslneehskqyrclsfqpecs
mkltplvlevfg

Timeline for d2hara1:

• d2hara1 first appeared in SCOP 1.73
  
• d2hara1 is called d2hara_ in SCOPe 2.01
  
• d2hara1 appears in the current release, SCOPe 2.08, called d2hara_